KPNA1 anticorps (N-Term)
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- Antigène Voir toutes KPNA1 Anticorps
- KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KPNA1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- NMEMAPGGVI TSDMIEMIFS KSPEQQLSAT QKFRKLLSKE PNPPIDEVIS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against KPNA1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human KPNA1
- Top Product
- Discover our top product KPNA1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 538 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
- Autre désignation
- KPNA1 (KPNA1 Produits)
- Synonymes
- anticorps IPOA5, anticorps NPI-1, anticorps RCH2, anticorps SRP1, anticorps AW494490, anticorps NPI1, anticorps Rch2, anticorps mSRP1, anticorps si:ch211-161h7.7, anticorps karyopherin subunit alpha 1, anticorps importin alpha-1 subunit, anticorps karyopherin (importin) alpha 1, anticorps karyopherin alpha 1 (importin alpha 5), anticorps KPNA1, anticorps Kpna1, anticorps EHI_124900, anticorps kpna1
- Sujet
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Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. KPNA1 interacts with RAG1 and may play a role in V(D)J recombination.Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IPOA5, NPI-1, RCH2, SRP1
Protein Interaction Partner: UBC, TAF9, CLK4, NUP50, ANP32B, XRN2, rev, TRMT61A, KCTD12, NPM1, GABPA, DCAF6, LIMCH1, HECW2, CLK3, HDAC2, HDAC1, GOPC, HDAC6, CRADD, LMO4, BCAR3, FOSL1, SKP2, ORC4, IL1RAP, AICDA, TP53BP1, KPNB1, RAG1, NOSIP, DCAF8, ANP32A, CAND1, COPS5, CUL1, CUL3, CUL
Protein Size: 538 - Poids moléculaire
- 60 kDa
- ID gène
- 3836
- NCBI Accession
- NM_002264, NP_002255
- UniProt
- P52294
- Pathways
- M Phase, Protein targeting to Nucleus
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