KPNA5 anticorps (C-Term)

N° du produit ABIN2785826

Cet anticorps Lapin Polyclonal détecte spécifiquement KPNA5 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Porc et Poisson zèbre (Danio rerio).

Aperçu rapide pour KPNA5 anticorps (C-Term) (ABIN2785826)

Antigène: KPNA5 (Karyopherin alpha 5 (Importin alpha 6) (KPNA5))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KPNA5 anticorps

Épitope: C-Term

Fonction: KPNA5 Antibody - C-terminal region

Séquence: TVMDSKIVQV ALNGLENILR LGEQESKQNG IGINPYCALI EEAYGLDKIE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 86%, Rat: 86%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against KPNA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human KPNA5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54679-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur KPNA5

Antigène: KPNA5 (Karyopherin alpha 5 (Importin alpha 6) (KPNA5))

Autre désignation: KPNA5

Sujet:

Targeted Subunit: alpha-6

Background Information: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus.The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Karyopherin alpha 5 (importin alpha 6)

Alternative Symbols: SRP6, IPOA6

Protein Name: Importin subunit alpha-6

Poids moléculaire: 61kDa

ID gène: 3841

NCBI Accession: NP_002260

UniProt: O15131

Pathways: Protein targeting to Nucleus