RPSA/Laminin Receptor anticorps (N-Term)
Aperçu rapide pour RPSA/Laminin Receptor anticorps (N-Term) (ABIN2785827)
Antigène
Voir toutes RPSA/Laminin Receptor (RPSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- QMKEEDVLKF LAAGTHLGGT NLDFQMEQYI YKRKSDGIYI INLKRTWEKL
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against Rpsa. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 295 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
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Autre désignation
- Rpsa
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Sujet
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Rpsa is required for the assembly and/or stability of the 40S ribosomal subunit. It is also required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. It slso functions as a cell surface receptor for laminin. It plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. It may play a role in cell fate determination and tissue morphogenesis. It also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. It enables malignant tumor cells to penetrate laminin tissue and vessel barriers and activates precursor thymic anti-OFA/iLRP specific cytotoxic T cell. It may induce CD8 T-suppressor cells secreting IL-10.
Alias Symbols: 67 kDa, 67lr, AL022858, Lamr, Lamr1, Lamrl1, MGC117921, MGC118614, MLR, P40, P40-3, P40-8
Protein Interaction Partner: Eed, Rara, Rpgrip1l, Tcf3,
Protein Size: 295 -
Poids moléculaire
- 32 kDa
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ID gène
- 16785
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NCBI Accession
- NM_011029, NP_035159
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UniProt
- P14206
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Antigène
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