RHOB anticorps (Middle Region)

N° du produit ABIN2785839

Cet anticorps anti-RHOB Polyclonal Lapin (ABIN2785839) détecte spécifiquement RHOB dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Porc, Mouton, Chien, Cobaye, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour RHOB anticorps (Middle Region) (ABIN2785839)

Antigène: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Porc, Mouton, Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RHOB anticorps

Épitope: Middle Region

Fonction: RHOB Antibody - middle region

Séquence: CPNVPIILVA NKKDLRSDEH VRTELARMKQ EPVRTDDGRA MAVRIQAYDY

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against RHOB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RHOB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54702-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RHOB

Antigène: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Autre désignation: RHOB

Sujet:

Background Information: RHOB mediates apoptosis in neoplastically transformed cells after DNA damage.RHOB is not essential for development but affects cell adhesion and growth factor signaling in transformed cells.RHOB plays a negative role in tumorigenesis as deletion causes tumor formation. RHOB is involved in intracellular protein trafficking of a number of proteins.RHOB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes.RHOB is also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.

Gene Name: Ras homolog family member B

Alternative Symbols: ARH6, ARHB, RHOH6, MST081, MSTP081

Protein Name: Rho-related GTP-binding protein RhoB

Poids moléculaire: 22kDa

ID gène: 388

NCBI Accession: NP_004031

UniProt: P62745