IDI1 anticorps (Middle Region)

N° du produit ABIN2785856

Cet anticorps Lapin Polyclonal détecte spécifiquement IDI1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Chien et Lapin.

Aperçu rapide pour IDI1 anticorps (Middle Region) (ABIN2785856)

Antigène: IDI1 (Isopentenyl-Diphosphate delta Isomerase 1 (IDI1))

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDI1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IDI1 anticorps

Épitope: Middle Region

Séquence: PLSNPAELEE SDALGVRRAA QRRLKAELGI PLEEVPPEEI NYLTRIHYKA

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against IDI1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human IDI1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 284 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IDI1

Antigène: IDI1 (Isopentenyl-Diphosphate delta Isomerase 1 (IDI1))

Autre désignation: IDI1

Sujet: IDI1 is a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-492 BE891119.1 50-541 493-1758 BX648472.1 1201-2466 1759-2150 BX537663.1 4550-4941
Alias Symbols: IPP1, IPPI1
Protein Interaction Partner: UBC, FN1, BARD1,
Protein Size: 284

Poids moléculaire: 32 kDa

ID gène: 3422

NCBI Accession: NM_004508, NP_004499

UniProt: Q13907