Histone Cluster 1, H1t (HIST1H1T) (Middle Region) anticorps

N° du produit ABIN2785870

L’anticorps anti-Histone Cluster 1, H1t Polyclonal Lapin est utilisé pour la détection de Histone Cluster 1, H1t dans des échantillons de Humain, Chien, Porc et Lapin. Il a été validé pour WB.

Aperçu rapide pour Histone Cluster 1, H1t (HIST1H1T) (Middle Region) anticorps (ABIN2785870)

Antigène: Histone Cluster 1, H1t (HIST1H1T)

Reactivité: Humain, Chien, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: Middle Region

Fonction: HIST1H1T Antibody - middle region

Séquence: KLSKKVIPKS TRSKAKKSVS AKTKKLVLSR DSKSPKTAKT NKRAKKPRAT

Homologie: Dog: 92%, Human: 100%, Pig: 86%, Rabbit: 93%

Attributs du produit: This is a rabbit polyclonal antibody against HIST1H1T. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HIST1H1T

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54761-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Histone Cluster 1, H1t (HIST1H1T)

Autre désignation: HIST1H1T

Sujet:

Background Information: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST1H1T is a member of the histone H1 family. Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Gene Name: Histone cluster 1, H1t

Alternative Symbols: H1t, H1.6, H1FT, HIST1H1T, dJ221C16.2

Protein Name: Histone H1t

Poids moléculaire: 22kDa

ID gène: 3010

NCBI Accession: NP_005314

UniProt: P22492