LOXL1 anticorps (Middle Region)

N° du produit ABIN2785879

Cet anticorps Lapin Polyclonal détecte spécifiquement LOXL1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Cheval, Porc et Poisson zèbre (Danio rerio).

Aperçu rapide pour LOXL1 anticorps (Middle Region) (ABIN2785879)

Antigène: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Cheval, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LOXL1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LOXL1 anticorps

Épitope: Middle Region

Séquence: YRPNQNGRGL PDLVPDPNYV QASTYVQRAH LYSLRCAAEE KCLASTAYAP

Homologie: Cow: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against LOXL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human LOXL1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 574 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur LOXL1

Antigène: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Autre désignation: LOXL1

Sujet: LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LOL, LOXL
Protein Interaction Partner: ATXN1, CUL2, FBLN5, ELN,
Protein Size: 574

Poids moléculaire: 53 kDa

ID gène: 4016

NCBI Accession: NM_005576, NP_005567

UniProt: Q08397