CCT5 anticorps (N-Term)
Aperçu rapide pour CCT5 anticorps (N-Term) (ABIN2785905)
Antigène
Voir toutes CCT5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- NDGATILSMM DVDHQIAKLM VELSKSQDDE IGDGTTGVVV LAGALLEEAE
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against CCT5. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CCT5
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 541 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CCT5 (Chaperonin Containing TCP1, Subunit 5 (Epsilon) (CCT5))
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Autre désignation
- CCT5
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Sujet
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CCT5 is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CCT-epsilon, CCTE, KIAA0098, TCP-1-epsilon
Protein Interaction Partner: SSSCA1, HUWE1, UBC, TP53, FUS, TUBG1, SUMO2, SUMO3, LGALS3BP, CDC20, NEDD1, MDM2, RNF2, CCT8, CCT2, CCT7, FBXO6, UBD, TERT, FBXW4, CDK9, CDK5, HDAC6, HDAC3, ILK, CDK2, PAN2, FAM86B2, PEX14, NOS2, ITGA4, FN1, ATF2, METTL21B, VCAM1, VCP, PACRG, AHCYL1, CCT6
Protein Size: 541 -
Poids moléculaire
- 60 kDa
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ID gène
- 22948
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NCBI Accession
- NM_012073, NP_036205
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UniProt
- P48643
Antigène
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