Peroxiredoxin 5 anticorps (Middle Region)

N° du produit ABIN2785911

Cité dans 1 publication. Cet anticorps anti-Peroxiredoxin 5 Polyclonal Lapin (ABIN2785911) détecte spécifiquement Peroxiredoxin 5 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chévre, Chien, Cobaye, Cheval, Mouton et Porc.

Aperçu rapide pour Peroxiredoxin 5 anticorps (Middle Region) (ABIN2785911)

Antigène: Peroxiredoxin 5 (PRDX5)

Reactivité: Humain, Souris, Rat, Chévre, Chien, Cobaye, Cheval, Mouton, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Peroxiredoxin 5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Peroxiredoxin 5 anticorps

Épitope: Middle Region

Fonction: PRDX5 Antibody - middle region

Séquence: TDLLLDDSLV SIFGNRRLKR FSMVVQDGIV KALNVEPDGT GLTCSLAPNI

Homologie: Dog: 86%, Goat: 79%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rat: 93%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PRDX5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PRDX5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54832-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Peroxiredoxin 5 (ABIN2785911)

Trujillo, Clippe, Manta, Ferrer-Sueta, Smeets, Declercq, Knoops, Radi: "Pre-steady state kinetic characterization of human peroxiredoxin 5: taking advantage of Trp84 fluorescence increase upon oxidation." dans: Archives of biochemistry and biophysics, Vol. 467, Issue 1, pp. 95-106, (2007) (PubMed).

Détails sur Peroxiredoxin 5

Antigène: Peroxiredoxin 5 (PRDX5)

Autre désignation: PRDX5

Sujet:

Background Information: PRDX5 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms.This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: Peroxiredoxin 5

Alternative Symbols: PLP, ACR1, B166, PRXV, PMP20, PRDX6, prx-V, SBBI10, AOEB166, HEL-S-55

Protein Name: Peroxiredoxin 5 EMBL AAI71733.1

Poids moléculaire: 14kDa

ID gène: 25824

NCBI Accession: NP_857635

UniProt: B7ZVW3

Pathways: Cell RedoxHomeostasis