GTPBP4 anticorps (C-Term)

N° du produit ABIN2785935

Cet anticorps anti-GTPBP4 est un anticorps Lapin Polyclonal détectant GTPBP4 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin et Cobaye.

Aperçu rapide pour GTPBP4 anticorps (C-Term) (ABIN2785935)

Antigène: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTPBP4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GTPBP4 anticorps

Épitope: C-Term

Séquence: MVKKAKTMMK NAQKKMNRLG KKGEADRHVF DMKPKHLLSG KRKAGKKDRR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GTPBP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human GTPBP4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 634 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GTPBP4

Antigène: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Autre désignation: GTPBP4

Sujet: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
Alias Symbols: CRFG, FLJ10686, FLJ10690, FLJ39774, NGB, NOG1
Protein Interaction Partner: SUMO3, UBC, POP1, PNMA2, PSME3, PRKRA, SUMO1, STAU1, NEDD8, EIF6, IFRD1, AZGP1, MRTO4, KCTD2, DICER1, SUZ12, EED, RNF2, CSNK2A2, CBX8, VCAM1, FN1, ESR1, UBD, CAND1, COPS5, SIRT7, SUMO2, EIF2AK2, OAS3, tat, TP53, YWHAG, LYAR, PINX1,
Protein Size: 634

Poids moléculaire: 74 kDa

ID gène: 23560

NCBI Accession: NM_012341, NP_036473

UniProt: Q9BZE4