Cytohesin 4 anticorps (N-Term)

N° du produit ABIN2785970

Cet anticorps anti-Cytohesin 4 Polyclonal Lapin (ABIN2785970) détecte spécifiquement Cytohesin 4 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc, Poisson zèbre (Danio rerio), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour Cytohesin 4 anticorps (N-Term) (ABIN2785970)

Antigène: Cytohesin 4 (CYTH4)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Poisson zèbre (Danio rerio), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cytohesin 4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cytohesin 4 anticorps

Épitope: N-Term

Fonction: PSCD4 Antibody - N-terminal region

Séquence: NKTAIGTYLG ERDPINLQVL QAFVDCHEFA NLNLVQALRQ FLWSFRLPGE

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 91%

Attributs du produit: This is a rabbit polyclonal antibody against PSCD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PSCD4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54947-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cytohesin 4

Antigène: Cytohesin 4 (CYTH4)

Autre désignation: PSCD4

Sujet:

Background Information: PSCD4 promotes guanine-nucleotide exchange on ARF1 and ARF5. PSCD4 promotes the activation of ARF through replacement of GDP with GTP.Pleckstrin homology, Sec7 and coiled/coil domains 4 (PSCD4) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The PSCD4 exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The PSCD4 and PSCD1 gene structures are very similar.

Gene Name: Cytohesin 4

Alternative Symbols: CYT4, PSCD4, DJ63G5.1, cytohesin-4

Protein Name: Cytohesin-4

Poids moléculaire: 46kDa

ID gène: 27128

NCBI Accession: NP_037517

UniProt: Q9UIA0