EDC4 anticorps (N-Term)
Aperçu rapide pour EDC4 anticorps (N-Term) (ABIN2786009)
Antigène
Voir toutes EDC4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- LQEKQVICLS GDDSSTCIGI LAKEVEIVAS SDSSISSKAR GSNKVKIQPV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against EDC4. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human EDC4
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 1401 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Synthesis, characterization, and antitumoral activity of polyoxometalate loaded starch nanocomplexes." dans: Journal of nanoscience and nanotechnology, Vol. 5, Issue 6, pp. 905-8, (2005) (PubMed).
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: "Synthesis, characterization, and antitumoral activity of polyoxometalate loaded starch nanocomplexes." dans: Journal of nanoscience and nanotechnology, Vol. 5, Issue 6, pp. 905-8, (2005) (PubMed).
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- EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
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Autre désignation
- EDC4
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Sujet
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In the process of mRNA degradation, EDC4 seems to play a role in mRNA decapping. It is the component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. EDC4 promotes complex formation between DCP1A and DCP2.It enhances the catalytic activity of DCP2 (in vitro).
Alias Symbols: Ge-1, HEDLS, RCD-8
Protein Interaction Partner: MDM2, DCP1B, DCP1A, UBC, DCP2, LGR4, WWOX, RPA3, RPA2, RPA1, BMI1, DIMT1, NELFB, IGF2BP3, G3BP1, EIF2B2, EIF2B3, RFC4, NMT1, ILF2, FKBP3, DDX1, ABCF1, ZFP36, YTHDC1, EDC3, vpu, GIT2, FBLN1, CCL5, UPF1, CRK, SIRT7, EIF2AK2, Edc4, Pds5a, tat,
Protein Size: 1401 -
Poids moléculaire
- 152 kDa
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ID gène
- 23644
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NCBI Accession
- NM_014329, NP_055144
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UniProt
- Q6P2E9
Antigène
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