HSPB8 anticorps (N-Term)
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- Antigène Voir toutes HSPB8 Anticorps
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HSPB8 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ADGQMPFSCH YPSRLRRDPF RDSPLSSRLL DDGFGMDPFP DDLTASWPDW
- Homologie
- Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against HSPB8. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HSPB8
- Top Product
- Discover our top product HSPB8 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 196 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
- Autre désignation
- HSPB8 (HSPB8 Produits)
- Synonymes
- anticorps CMT2L, anticorps DHMN2, anticorps E2IG1, anticorps H11, anticorps HMN2, anticorps HMN2A, anticorps HSP22, anticorps MGC64408, anticorps hsc70, anticorps wu:fb01g06, anticorps wu:fi48b06, anticorps fc09c11, anticorps wu:fc04b04, anticorps wu:fc09c11, anticorps zgc:64202, anticorps AU018630, anticorps AW413033, anticorps Cryac, anticorps D5Ucla4, anticorps H11K, anticorps HSP20-like, anticorps Hsp22, anticorps heat shock protein family B (small) member 8, anticorps heat shock protein family B (small) member 8 L homeolog, anticorps heat shock protein 8, anticorps heat shock protein b8, anticorps HSPB8, anticorps hspb8.L, anticorps hspa8, anticorps hspb8, anticorps Hspb8
- Sujet
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HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Protein Interaction Partner: QRICH1, HSPB7, DUSP12, BAG3, ASB4, UBC, CIAPIN1, DSTN, HSPB6, HSPB3, SNCA, CRYAB, HSPB1, HSPB8, MAPK3, PRKCA, CSNK2A1, HSPB2,
Protein Size: 196 - Poids moléculaire
- 21 kDa
- ID gène
- 26353
- NCBI Accession
- NM_014365, NP_055180
- UniProt
- Q9UJY1
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