RABGEF1 anticorps (N-Term)

N° du produit ABIN2786039

Cet anticorps anti-RABGEF1 Polyclonal Lapin (ABIN2786039) détecte spécifiquement RABGEF1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cheval, Poisson zèbre (Danio rerio), Lapin et Cobaye.

Aperçu rapide pour RABGEF1 anticorps (N-Term) (ABIN2786039)

Antigène: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cheval, Poisson zèbre (Danio rerio), Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RABGEF1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RABGEF1 anticorps

Épitope: N-Term

Séquence: MSLKSERRGI HVDQSDLLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against RABGEF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RABGEF1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 491 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RABGEF1

Antigène: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Autre désignation: RABGEF1

Sujet: RABGEF1 forms a complex with rabaptin-5 (RABPT5, MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A, MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).
Alias Symbols: FLJ32302, RABEX5, rabex-5
Protein Interaction Partner: TRIM15, CIPC, ZC2HC1C, TRIM54, RABGEF1, BLOC1S6, TXN2, THOC1, DAZAP2, UBC, TEAD4, RABEP1, DGCR6, TNKS1BP1, ROCK2, SLMAP, MON1A, RNF11, MON1B, RAB21, UBE2D3, UBE2D1, RAB5A, L1CAM, EEA1, ESR1, EGFR, RAB22A, GGA1, MAPK1, HRAS, YWHAG, YWHAB, KXD1, GGA2, RNF16
Protein Size: 491

Poids moléculaire: 57 kDa

ID gène: 27342

NCBI Accession: NM_014504, NP_055319

UniProt: A8K3R3

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process