FAM120A anticorps (Middle Region)
Aperçu rapide pour FAM120A anticorps (Middle Region) (ABIN2786049)
Antigène
Voir toutes FAM120A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- FAM120A Antibody - middle region
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Séquence
- SGGATNHISG NKIGWEKTGS HSEPQARGDP GDQTKAEGSS TASSGSQLAE
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Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 92%, Rat: 85%
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Attributs du produit
- This is a rabbit polyclonal antibody against FAM120A. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human FAM120A
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55089-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- FAM120A (Family with Sequence Similarity 120A (FAM120A))
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Autre désignation
- FAM120A
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Sujet
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Background Information: FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Gene Name: Family with sequence similarity 120A
Alternative Symbols: OSSA, C9orf10, HBVPTPAP
Protein Name: Constitutive coactivator of PPAR-gamma-like protein 1
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Poids moléculaire
- 122kDa
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ID gène
- 23196
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NCBI Accession
- NP_055427
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UniProt
- Q9NZB2
Antigène
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