AGTPBP1 anticorps (C-Term)

N° du produit ABIN2786096

Cet anticorps Lapin Polyclonal détecte spécifiquement AGTPBP1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Cheval, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio) et Cobaye.

Aperçu rapide pour AGTPBP1 anticorps (C-Term) (ABIN2786096)

Antigène: AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGTPBP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AGTPBP1 anticorps

Épitope: C-Term

Fonction: Agtpbp1 Antibody - C-terminal region

Séquence: GMQPLMYSVQ EALNARPWWI RMGTDICYYK NHFSRSSVAA GGQKGKSYYT

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against Agtpbp1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Agtpbp1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55206-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur AGTPBP1

Antigène: AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))

Autre désignation: Agtpbp1

Sujet:

Background Information: Agtpbp1 is a metallocarboxypeptidase that mediates deglutamylation of target proteins. It catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. It also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Agtpbp1 acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Deglutamylation plays a key role in cerebellar Purkinje cell differentiation, accumulation of tubulin polyglutamylation causing neurodegeneration.

Alternative Symbols: N, at, Ccp, pcd, CCP1, Nna1, atms, nmf243, 1700020N17Rik, 2310001G17Rik, 2900054O13Rik, 4930445M19Rik, 5730402G09Rik

Poids moléculaire: 128kDa

ID gène: 67269

NCBI Accession: NP_075817

UniProt: Q9UPW5

Pathways: Proton Transport