COPG anticorps (N-Term)
Aperçu rapide pour COPG anticorps (N-Term) (ABIN2786156)
Antigène
Voir toutes COPG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- MLKKFDKKDE ESGGGSNPFQ HLEKSAVLQE ARVFNETPIN PRKCAHILTK
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against COPG. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human COPG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 874 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- COPG (Coatomer Protein Complex, Subunit gamma (COPG))
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Autre désignation
- COPG
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Sujet
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The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Alias Symbols: COPG1, FLJ21068, COPG
Protein Interaction Partner: HUWE1, UBC, SUMO2, NUDCD1, RNF2, RABGAP1, COPZ1, COPE, TELO2, TTI1, ARHGEF10, COPB2, TLE3, TCP1, RUFY1, DDB2, COPB1, ARCN1, UBD, NPM1, PPBP, FN1, COPG2, COPA, COPZ2, COPG1, SACM1L, TMED10, SIRT7, H2AFX, MYC, ATG101, PMS2, KEAP1, GBF1, TAPBP, PTGES3, RHOQ,
Protein Size: 874 -
Poids moléculaire
- 98 kDa
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ID gène
- 22820
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NCBI Accession
- NM_016128, NP_057212
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UniProt
- Q9Y678
Antigène
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