CCDC11 anticorps (N-Term)

N° du produit ABIN2786216

Cet anticorps Lapin Polyclonal détecte spécifiquement CCDC11 dans WB. Il présente une réactivité avec des échantillons de Humain, Cobaye, Cheval, Porc, Boeuf (Vache) et Chien. Il a été cité dans 2+ publications.

Aperçu rapide pour CCDC11 anticorps (N-Term) (ABIN2786216)

Antigène: CCDC11 (Coiled-Coil Domain Containing 11 (CCDC11))

Reactivité: Humain, Cobaye, Cheval, Porc, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC11 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CCDC11 anticorps

Épitope: N-Term

Fonction: CFAP53 Antibody - N-terminal region

Séquence: YSQRFGTVQR EVKGPTPKVV IVRSKPPKGQ GAEHHLERIR RSHQKHNAIL

Homologie: Cow: 93%, Dog: 79%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Pig: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CCDC11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CCDC11

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55454-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CCDC11 (ABIN2786216)

Perles, Cinnamon, Ta-Shma, Shaag, Einbinder, Rein, Elpeleg: "A human laterality disorder associated with recessive CCDC11 mutation." dans: Journal of medical genetics, Vol. 49, Issue 6, pp. 386-90, (2012) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." dans: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Détails sur CCDC11

Antigène: CCDC11 (Coiled-Coil Domain Containing 11 (CCDC11))

Autre désignation: CFAP53

Sujet:

Background Information: This gene belongs to the CFAP53 family. It was found to be differentially expressed by the ciliated cells of frog epidermis and in skin fibroblasts from human. Mutations in this gene are associated with visceral heterotaxy-6, which implicates this gene in determination of left-right asymmetric patterning.

Gene Name: cilia and flagella associated protein 53

Alternative Symbols: HTX6, CCDC11

Protein Name: cilia- and flagella-associated protein 53

Poids moléculaire: 62kDa

ID gène: 220136

NCBI Accession: NP_659457

UniProt: Q96M91