FBXW8 anticorps (Middle Region)

N° du produit ABIN2786275

Cité dans 1 publication. Cet anticorps anti-FBXW8 Polyclonal Lapin (ABIN2786275) détecte spécifiquement FBXW8 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Lapin, Cobaye, Cheval et Chien.

Aperçu rapide pour FBXW8 anticorps (Middle Region) (ABIN2786275)

Antigène: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Cobaye, Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FBXW8 anticorps

Épitope: Middle Region

Fonction: FBXW8 Antibody - middle region

Séquence: MNQKLWEVYS GHPVQHISFS SHSLITANVP YQTVMRNADL DSFTTHRRHR

Homologie: Cow: 83%, Dog: 92%, Guinea Pig: 83%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against FBXW8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FBXW8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55585-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FBXW8 (ABIN2786275)

Lin, Fu, Zhao, Lin, Zou, Liu, Zhu, Wang, Yu: "Fbxw8 is involved in the proliferation of human choriocarcinoma JEG-3 cells." dans: Molecular biology reports, Vol. 38, Issue 3, pp. 1741-7, (2011) (PubMed).

Détails sur FBXW8

Antigène: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Autre désignation: FBXW8

Sujet:

Background Information: FBXW8 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW8 contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class.This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: F-box and WD repeat domain containing 8

Alternative Symbols: FBW6, FBW8, FBX29, FBXW6, FBXO29

Protein Name: F-box/WD repeat-containing protein 8

Poids moléculaire: 67kDa

ID gène: 26259

NCBI Accession: NP_699179

UniProt: Q8N3Y1