COX18 anticorps (Middle Region)

N° du produit ABIN2786331

L’anticorps anti-COX18 Polyclonal Lapin est utilisé pour la détection de COX18 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin et Porc. Il a été validé pour WB.

Aperçu rapide pour COX18 anticorps (Middle Region) (ABIN2786331)

Antigène: COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COX18 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-COX18 anticorps

Épitope: Middle Region

Fonction: COX18 Antibody - middle region

Séquence: LCSSFVGLSQ NLLLRSPGFR QLCRIPSTKS DSETPYKDIF AAFNTKFISR

Homologie: Cow: 79%, Dog: 79%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 86%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against COX18. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human COX18

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55716-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur COX18

Antigène: COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))

Autre désignation: COX18

Sujet:

Background Information: COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2, MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1248 AY957565.1 1-1248 1249-4523 AC095053.3 75071-78345 c

Gene Name: COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)

Alternative Symbols: COX18HS

Protein Name: Mitochondrial inner membrane protein COX18

Poids moléculaire: 37kDa

ID gène: 285521

NCBI Accession: NP_776188

UniProt: Q8N8Q8