HIPK1 anticorps (Middle Region)
Aperçu rapide pour HIPK1 anticorps (Middle Region) (ABIN2786406)
Antigène
Voir toutes HIPK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- PLNLSQNQQS SAAPTSQERS SNPAPRRQQA FVAPLSQAPY TFQHGSPLHS
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Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against HIPK1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human HIPK1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 1210 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
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Autre désignation
- HIPK1
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Sujet
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HIPK1 may play a role as a corepressor for homeodomain transcription factors. HIPK1 phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. HIPK1 may be involved in malignant squamous cell tumor formation.The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.
Alias Symbols: KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2
Protein Interaction Partner: FHL3, HIPK1, DDX54, HAX1, NEB, A2M, PRPF40A, UBC, SKIL, PARK7, ATP13A2, RASSF5, SIAH1, UBE2I, GLUL, SNIP1, DAXX, NKX2-5, TP53, RUNX1, HOXD4,
Protein Size: 1210 -
Poids moléculaire
- 131 kDa
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ID gène
- 204851
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NCBI Accession
- NM_198268, NP_938009
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UniProt
- Q86Z02
Antigène
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