HIPK1 anticorps (Middle Region)

N° du produit ABIN2786406

Détail du produit anti-HIPK1 anticorps

Antigène: HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIPK1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PLNLSQNQQS SAAPTSQERS SNPAPRRQQA FVAPLSQAPY TFQHGSPLHS

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against HIPK1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HIPK1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1210 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HIPK1

Antigène: HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

Autre désignation: HIPK1 (HIPK1 Produits)

Synonymes: anticorps HIPK1, anticorps myak, anticorps nbak2, anticorps hipk1, anticorps Myak, anticorps Nbak2, anticorps 1110062K04Rik, anticorps homeodomain interacting protein kinase 1, anticorps homeodomain interacting protein kinase 1 L homeolog, anticorps homeodomain interacting protein kinase 1 S homeolog, anticorps HIPK1, anticorps hipk1.L, anticorps hipk1, anticorps hipk1.S, anticorps Hipk1

Sujet: HIPK1 may play a role as a corepressor for homeodomain transcription factors. HIPK1 phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. HIPK1 may be involved in malignant squamous cell tumor formation.The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.
Alias Symbols: KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2
Protein Interaction Partner: FHL3, HIPK1, DDX54, HAX1, NEB, A2M, PRPF40A, UBC, SKIL, PARK7, ATP13A2, RASSF5, SIAH1, UBE2I, GLUL, SNIP1, DAXX, NKX2-5, TP53, RUNX1, HOXD4,
Protein Size: 1210

Poids moléculaire: 131 kDa

ID gène: 204851

NCBI Accession: NM_198268, NP_938009

UniProt: Q86Z02