PPOX anticorps (N-Term)

N° du produit ABIN2786509

Il existe 1 publication pour ce produit. L’anticorps anti-PPOX Polyclonal Lapin est utilisé pour la détection de PPOX dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Cheval, Chien et Porc. Il a été validé pour WB.

Aperçu rapide pour PPOX anticorps (N-Term) (ABIN2786509)

Antigène: PPOX (Protoporphyrinogen Oxidase (PPOX))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Cheval, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPOX est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PPOX anticorps

Épitope: N-Term

Fonction: PPOX Antibody - N-terminal region

Séquence: SSERLGGWIR SVRGPNGAIF ELGPRGIRPA GALGARTLLL VSELGLDSEV

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PPOX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PPOX

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56095-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PPOX (ABIN2786509)

de Vooght, van Wijk, van Solinge: "GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX." dans: Gene, Vol. 409, Issue 1-2, pp. 83-91, (2008) (PubMed).

Détails sur PPOX

Antigène: PPOX (Protoporphyrinogen Oxidase (PPOX))

Autre désignation: PPOX

Sujet:

Background Information: PPOX catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX..This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Gene Name: Protoporphyrinogen oxidase

Alternative Symbols: VP, PPO, V290M

Protein Name: Protoporphyrinogen oxidase

Poids moléculaire: 51kDa

ID gène: 5498

NCBI Accession: NP_000300

UniProt: P50336

Pathways: Synaptic Membrane, Feeding Behaviour