Rhotekin anticorps (N-Term)

N° du produit ABIN2786576

Cet anticorps anti-Rhotekin Polyclonal Lapin (ABIN2786576) détecte spécifiquement Rhotekin dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour Rhotekin anticorps (N-Term) (ABIN2786576)

Antigène: Rhotekin (RTKN)

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Rhotekin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Rhotekin anticorps

Épitope: N-Term

Fonction: RTKN Antibody - N-terminal region

Séquence: DSGPPAERSP CRGRVCISDL RIPLMWKDTE YFKNKGDLHR WAVFLLLQLG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against RTKN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RTKN

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56210-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Rhotekin

Antigène: Rhotekin (RTKN)

Autre désignation: RTKN

Sujet:

Background Information: RTKN mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. RTKN may play a novel role in the organization of septin structures.This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: Rhotekin

Alternative Symbols: -

Protein Name: Rhotekin

Poids moléculaire: 63kDa

ID gène: 6242

NCBI Accession: NP_001015055

UniProt: Q9BST9