PAIP2 anticorps (N-Term)

N° du produit ABIN2786594

Détail du produit anti-PAIP2 anticorps

Antigène: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Porc, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAIP2 est non-conjugé

Application: Western Blotting (WB)

Séquence: MKDPSRSSTS PSIINEDVII NGHSHEDDNP FAEYMWMENE EEFNRQIEEE

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PAIP2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 127 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PAIP2

Antigène: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Autre désignation: PAIP2 (PAIP2 Produits)

Synonymes: anticorps PAIP2A, anticorps DKFZp469O1314, anticorps 2310050K10Rik, anticorps AU045972, anticorps paip2, anticorps poly(A) binding protein interacting protein 2, anticorps polyadenylate-binding protein-interacting protein 2, anticorps poly(A) binding protein interacting protein 2B L homeolog, anticorps PAIP2, anticorps Paip2, anticorps paip2b.L

Sujet: PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. It displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Alias Symbols: MGC72018, PAIP2A
Protein Interaction Partner: PABPC1, BAG3, RPL11, IGBP1, APP, UBC, UBR5, ELAVL1,
Protein Size: 127

Poids moléculaire: 14 kDa

ID gène: 51247

NCBI Accession: NM_016480, NP_057564

UniProt: Q9BPZ3