ACO2 anticorps (N-Term)

N° du produit ABIN2786627

Il existe 2+ publications pour ce produit. L’anticorps anti-ACO2 Polyclonal Lapin est utilisé pour la détection de ACO2 dans des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache), Saccharomyces cerevisiae, Cobaye, Cheval et Lapin. Il a été validé pour WB.

Aperçu rapide pour ACO2 anticorps (N-Term) (ABIN2786627)

Antigène: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Saccharomyces cerevisiae, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACO2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ACO2 anticorps

Épitope: N-Term

Fonction: ACO2 Antibody - N-terminal region

Séquence: LQFISSGLSK VAVPSTIHCD HLIEAQVGGE KDLRRAKDIN QEVYNFLATA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ACO2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ACO2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56301-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ACO2 (ABIN2786627)

Schauer, Freund, Prenni, Curthoys: "Proteomic profiling and pathway analysis of the response of rat renal proximal convoluted tubules to metabolic acidosis." dans: American journal of physiology. Renal physiology, Vol. 305, Issue 5, pp. F628-40, (2013) (PubMed).

Freund, Prenni, Curthoys: "Response of the mitochondrial proteome of rat renal proximal convoluted tubules to chronic metabolic acidosis." dans: American journal of physiology. Renal physiology, Vol. 304, Issue 2, pp. F145-55, (2013) (PubMed).

Détails sur ACO2

Antigène: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Autre désignation: ACO2

Sujet:

Background Information: ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Aconitase 2, mitochondrial

Alternative Symbols: ICRD, OCA8, OPA9, ACONM, HEL-S-284

Protein Name: Aconitate hydratase, mitochondrial

Poids moléculaire: 82kDa

ID gène: 50

NCBI Accession: NP_001089

UniProt: Q99798