PIM1 anticorps (N-Term)

N° du produit ABIN503950

Cet anticorps Lapin Polyclonal détecte spécifiquement PIM1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Cheval, Mouton, Boeuf (Vache), Chien, Lapin et Cobaye.

Aperçu rapide pour PIM1 anticorps (N-Term) (ABIN503950)

Antigène: PIM1 (Pim-1 Oncogene (PIM1))

Reactivité: Humain, Souris, Rat, Cheval, Mouton, Boeuf (Vache), Chien, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIM1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PIM1 anticorps

Épitope: N-Term

Séquence: MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PIM1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PIM1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 313 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PIM1

Antigène: PIM1 (Pim-1 Oncogene (PIM1))

Autre désignation: PIM1

Sujet: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.
Alias Symbols: PIM
Protein Interaction Partner: FXR2, NHLH1, FH, BEND7, HEXIM2, BANP, TFPT, ZBTB1, UBC, APP, MARK3, HSP90AA1, HSPA4, PIM1, MDM2, ELAVL1, FZR1, SKP2, PPP2R5E, PPP2R4, PPP2CA, PIN1, CDC34, CDC20, ABCB1, HIST2H3C, MYC, MAX, SNX6, CBX1, CBX3, BAD, HIST3H3, SND1, PTPRO, NFATC1, SHMT1, EPHA3,
Protein Size: 313

Poids moléculaire: 36 kDa

ID gène: 5292

NCBI Accession: NM_002648, NP_002639

Pathways: Glycosaminoglycan Metabolic Process