PRELP anticorps (Middle Region)
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- Antigène Voir toutes PRELP Anticorps
- PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))
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Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PRELP est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- SNKIETIPNG YFKSFPNLAF IRLNYNKLTD RGLPKNSFNI SNLLVLHLSH
- Homologie
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against PRELP. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PRELP
- Top Product
- Discover our top product PRELP Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 382 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))
- Autre désignation
- PRELP (PRELP Produits)
- Synonymes
- anticorps 7330409J17Rik, anticorps SLRR2A, anticorps MST161, anticorps MSTP161, anticorps proline arginine-rich end leucine-rich repeat, anticorps proline and arginine rich end leucine rich repeat protein, anticorps Prelp, anticorps PRELP
- Sujet
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PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
Alias Symbols: MGC45323, MST161, MSTP161, SLRR2A
Protein Interaction Partner: Dlg4, HSPG2, FBLN2, FN1, NID1, COL1A1, COL2A1, NID2,
Protein Size: 382 - Poids moléculaire
- 42 kDa
- ID gène
- 5549
- NCBI Accession
- NM_002725, NP_002716
- UniProt
- P51888
- Pathways
- Glycosaminoglycan Metabolic Process
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