RANGAP1 anticorps (N-Term)

N° du produit ABIN2786743

Cité dans 1 publication. Cet anticorps anti-RANGAP1 Polyclonal Lapin (ABIN2786743) détecte spécifiquement RANGAP1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour RANGAP1 anticorps (N-Term) (ABIN2786743)

Antigène: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANGAP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RANGAP1 anticorps

Épitope: N-Term

Fonction: RANGAP1 Antibody - N-terminal region

Séquence: MASEDIAKLA ETLAKTQVAG GQLSFKGKSL KLNTAEDAKD VIKEIEDFDS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RANGAP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RANGAP1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56509-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RANGAP1 (ABIN2786743)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur RANGAP1

Antigène: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Autre désignation: RANGAP1

Sujet:

Background Information: RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGA

Gene Name: Ran GTPase activating protein 1

Alternative Symbols: SD, Fug1, RANGAP

Protein Name: Ran GTPase-activating protein 1

Poids moléculaire: 63kDa

ID gène: 5905

NCBI Accession: NP_002874

UniProt: P46060

Pathways: M Phase, Protein targeting to Nucleus