SCP2 anticorps (Middle Region)

N° du produit ABIN2786761

Cet anticorps Lapin Polyclonal détecte spécifiquement SCP2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cobaye, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour SCP2 anticorps (Middle Region) (ABIN2786761)

Antigène: SCP2 (Sterol Carrier Protein 2 (SCP2))

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SCP2 anticorps

Épitope: Middle Region

Séquence: NHKHSVNNPY SQFQDEYSLD EVMASKEVFD FLTILQCCPT SDGAAAAILA

Homologie: Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SCP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SCP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 322 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SCP2

Antigène: SCP2 (Sterol Carrier Protein 2 (SCP2))

Autre désignation: SCP2

Sujet: SCP2 protein is thought to be an intracellular lipid transfer protein. SCP2 is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis.This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.
Alias Symbols: DKFZp686C12188, DKFZp686D11188, NLTP, NSL-TP, SCPX, SCP-2, SCP-X, SCP-CHI
Protein Interaction Partner: TRIP13, UBC, PEX5, MPLKIP, MRRF, SUGP1, MRPS28, TBL2, SRRM2, RAB31, SEPT9, TIMM44, ECI2, SCO2, AGPS, STX7, UBL4A, VDAC3, VDAC2, RRBP1, RBMS1, NDUFA7, IDH3G, HSD17B4, ACAA1, RAB8A, ELAVL1, CACNA1A, ACAA2, EHHADH, CAV1, ACOX1, PITPNA,
Protein Size: 322

Poids moléculaire: 35 kDa

ID gène: 6342

NCBI Accession: NM_001007098, NP_001007099

UniProt: Q6NXF4

Pathways: C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process