PKC eta anticorps (N-Term)

N° du produit ABIN2786852

Cet anticorps Lapin Polyclonal détecte spécifiquement PKC eta dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Cheval, Poisson zèbre (Danio rerio) et Porc.

Aperçu rapide pour PKC eta anticorps (N-Term) (ABIN2786852)

Antigène: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Cheval, Poisson zèbre (Danio rerio), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC eta est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PKC eta anticorps

Épitope: N-Term

Fonction: PRKCH Antibody - N-terminal region

Séquence: KKGHQLLDPY LTVSVDQVRV GQTSTKQKTN KPTYNEEFCA NVTDGGHLEL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against PRKCH. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCH

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56703-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PKC eta

Antigène: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Autre désignation: PRKCH

Sujet:

Background Information: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

Gene Name: Protein kinase C, eta

Alternative Symbols: PKCL, PKC-L, PRKCL, nPKC-eta

Protein Name: Protein kinase C eta type

Poids moléculaire: 78 kDa

ID gène: 5583

NCBI Accession: NP_006246

UniProt: P24723

Pathways: Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling