VPS36 anticorps (N-Term)

N° du produit ABIN2786923

Cet anticorps anti-VPS36 Polyclonal Lapin (ABIN2786923) détecte spécifiquement VPS36 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour VPS36 anticorps (N-Term) (ABIN2786923)

Antigène: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS36 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-VPS36 anticorps

Épitope: N-Term

Fonction: Vps36 Antibody - N-terminal region

Séquence: SNKEPGPFQS SKNSYIRLSF KEHGQIEFYR RLSEEMTQRR WETVPVSQSL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Vps36. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56827-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur VPS36

Antigène: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Autre désignation: Vps36

Sujet:

Background Information: Vps36 is a component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.

Gene Name: Vacuolar protein sorting 36 (yeast)

Alternative Symbols: Eap, Eap45, 1700010A24Rik, 2210415M20Rik, 2810408E15Rik

Protein Name: Vacuolar protein-sorting-associated protein 36

Poids moléculaire: 42kDa

ID gène: 70160

NCBI Accession: NP_081614

UniProt: Q91XD6