PNRC2 anticorps (Middle Region)

N° du produit ABIN2787028

Cet anticorps Lapin Polyclonal détecte spécifiquement PNRC2 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Lapin, Cobaye, Cheval, Boeuf (Vache), Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour PNRC2 anticorps (Middle Region) (ABIN2787028)

Antigène: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Reactivité: Humain, Rat, Souris, Lapin, Cobaye, Cheval, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNRC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PNRC2 anticorps

Épitope: Middle Region

Séquence: NQSWNSSLSG PRLLFKSQAN QNYAGAKFSE PPSPSVLPKP PSHWVPVSFN

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PNRC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PNRC2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 139 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PNRC2

Antigène: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Autre désignation: PNRC2

Sujet: PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery.PNRC2 may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. PNRC2 is required for UPF1/RENT1 localization to the P-body. PNRC2 also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure.
Alias Symbols: FLJ20312, MGC99541
Protein Interaction Partner: DCP1A, ESRRG, UBC, SF1, GLOD4, SPAG9, ZBTB48, XRCC6, RORA, RARG, HNF4G, HNF4A, NR5A2, ESR2, ESR1, ZBTB16, RORB, ESRRA, RARA, AR, NR5A1,
Protein Size: 139

Poids moléculaire: 15 kDa

ID gène: 55629

NCBI Accession: NM_017761, NP_060231

UniProt: Q9NPJ4