PNRC2 anticorps (Middle Region)

N° du produit ABIN2787028

Détail du produit anti-PNRC2 anticorps

Antigène: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Lapin, Cobaye, Cheval, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNRC2 est non-conjugé

Application: Western Blotting (WB)

Séquence: NQSWNSSLSG PRLLFKSQAN QNYAGAKFSE PPSPSVLPKP PSHWVPVSFN

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PNRC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PNRC2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 139 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PNRC2

Antigène: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Autre désignation: PNRC2 (PNRC2 Produits)

Synonymes: anticorps 0610011E17Rik, anticorps D4Bwg0593e, anticorps wu:cegs2777, anticorps wu:fb51a04, anticorps wu:fb81a06, anticorps wu:fd19g06, anticorps proline rich nuclear receptor coactivator 2, anticorps proline-rich nuclear receptor coactivator 2, anticorps PNRC2, anticorps Pnrc2, anticorps pnrc2

Sujet: PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery.PNRC2 may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. PNRC2 is required for UPF1/RENT1 localization to the P-body. PNRC2 also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure.
Alias Symbols: FLJ20312, MGC99541
Protein Interaction Partner: DCP1A, ESRRG, UBC, SF1, GLOD4, SPAG9, ZBTB48, XRCC6, RORA, RARG, HNF4G, HNF4A, NR5A2, ESR2, ESR1, ZBTB16, RORB, ESRRA, RARA, AR, NR5A1,
Protein Size: 139

Poids moléculaire: 15 kDa

ID gène: 55629

NCBI Accession: NM_017761, NP_060231

UniProt: Q9NPJ4