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Tescalcin anticorps (C-Term)

TESC Reactivité: Humain, Souris, Rat, Cheval, Chien, Cobaye, Lapin, Boeuf (Vache), Saccharomyces cerevisiae WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2787042
  • Antigène Voir toutes Tescalcin (TESC) Anticorps
    Tescalcin (TESC)
    Épitope
    • 8
    • 8
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 33
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Cheval, Chien, Cobaye, Lapin, Boeuf (Vache), Saccharomyces cerevisiae
    Hôte
    • 33
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Tescalcin est non-conjugé
    Application
    • 23
    • 19
    • 14
    • 13
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    DSDGRITLEE YRNVVEELLS GNPHIEKESA RSIADGAMME AASVCMGQME
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%
    Attributs du produit
    This is a rabbit polyclonal antibody against TESC. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human TESC
    Top Product
    Discover our top product TESC Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Tescalcin (TESC)
    Autre désignation
    TESC (TESC Produits)
    Synonymes
    anticorps TSC, anticorps chp3, anticorps CHP3, anticorps 1010001A17Rik, anticorps 2410011K10Rik, anticorps TE-1, anticorps RGD1566317, anticorps tescalcin, anticorps tescalcin L homeolog, anticorps tesc, anticorps TESC, anticorps Tesc, anticorps tesc.L
    Sujet
    TESC functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. It promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane and promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. It is essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. It is also involved in granulocytic differentiation in a ERK-dependent manner and inhibits the phosphatase activity of calcineurin.
    Alias Symbols: CHP3, TSC
    Protein Interaction Partner: WBP11, UBC, CCDC91, HMG20A, TESC, RAI1, DYNLT3, SLC9A1,
    Protein Size: 214
    Poids moléculaire
    23 kDa
    ID gène
    54997
    NCBI Accession
    NM_017899, NP_060369
    UniProt
    Q96BS2
    Pathways
    Proton Transport
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