Tescalcin anticorps (C-Term)

N° du produit ABIN2787042

Cet anticorps anti-Tescalcin Polyclonal Lapin (ABIN2787042) détecte spécifiquement Tescalcin dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache) et Saccharomyces cerevisiae.

Aperçu rapide pour Tescalcin anticorps (C-Term) (ABIN2787042)

Antigène: Tescalcin (TESC)

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tescalcin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Tescalcin anticorps

Épitope: C-Term

Fonction: TESC Antibody - C-terminal region

Séquence: DSDGRITLEE YRNVVEELLS GNPHIEKESA RSIADGAMME AASVCMGQME

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%

Attributs du produit: This is a rabbit polyclonal antibody against TESC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TESC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57060-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Tescalcin

Antigène: Tescalcin (TESC)

Autre désignation: TESC

Sujet:

Background Information: TESC functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+  exchange activity. It promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane and promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. It is essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. It is also involved in granulocytic differentiation in a ERK-dependent manner and inhibits the phosphatase activity of calcineurin.

Gene Name: tescalcin

Alternative Symbols: TSC, CHP3

Protein Name: Calcineurin B homologous protein 3

Poids moléculaire: 23kDa

ID gène: 54997

NCBI Accession: NP_060369

UniProt: Q96BS2

Pathways: Proton Transport