Members of the F-box protein family, such as FBXO34, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Alias Symbols: CGI-301, DKFZp547C162, FLJ20725, Fbx34, MGC126434, MGC126435
Protein Interaction Partner: KRT40, MTUS2, MDFI, CUL1, UBC, HSP90AA1, TGFBR2, TGFBR1, SKP1, SMAD4,
Protein Size: 711