CDCA7L anticorps (Middle Region)
Aperçu rapide pour CDCA7L anticorps (Middle Region) (ABIN2787158)
Antigène
Voir toutes CDCA7L AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- PPCRGICNCS YCRKRDGRCA TGILIHLAKF YGYDNVKEYL ESLQKELVED
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 90%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against CDCA7L. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CDCA7L
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 420 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))
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Autre désignation
- CDCA7L
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Sujet
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CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter.CDCA7L plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. CDCA7L is involved in apoptotic signaling pathways. CDCA7L may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Alias Symbols: DKFZp762L0311, JPO2, R1, RAM2
Protein Interaction Partner: KRTAP10-7, TRIM42, MORN3, BEND7, FAM9B, DEDD2, SSX2IP, ING5, TRAF3IP3, CEP70, CCDC33, CARD9, PRDM14, ZNF250, UTP3, CTNNBL1, ZNF821, CDCA7L, TFPT, ABT1, PRPF31, PPP1R16B, EIF4A3, STX11, UBL4A, TADA2A, NOP2, MFAP1, MDFI, LMO1, DAXX, BYSL, ANKRD11, SUV39H1,
Protein Size: 420 -
Poids moléculaire
- 46 kDa
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ID gène
- 55536
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NCBI Accession
- NM_001127370, NP_001120842
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UniProt
- B3KTR5
Antigène
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