CDCA7L anticorps (Middle Region)

N° du produit ABIN2787158

Détail du produit anti-CDCA7L anticorps

Antigène: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDCA7L est non-conjugé

Application: Western Blotting (WB)

Séquence: PPCRGICNCS YCRKRDGRCA TGILIHLAKF YGYDNVKEYL ESLQKELVED

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 90%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CDCA7L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CDCA7L

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 420 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDCA7L

Antigène: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Autre désignation: CDCA7L (CDCA7L Produits)

Synonymes: anticorps ram2, anticorps MGC154777, anticorps BC006933, anticorps JPO2, anticorps R1, anticorps RAM2, anticorps RAPGEF5, anticorps cell division cycle associated 7 like, anticorps cell division cycle associated 7 like L homeolog, anticorps cell division cycle-associated 7-like protein, anticorps CDCA7L, anticorps cdca7l.L, anticorps LOC100454683, anticorps Cdca7l

Sujet: CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter.CDCA7L plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. CDCA7L is involved in apoptotic signaling pathways. CDCA7L may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Alias Symbols: DKFZp762L0311, JPO2, R1, RAM2
Protein Interaction Partner: KRTAP10-7, TRIM42, MORN3, BEND7, FAM9B, DEDD2, SSX2IP, ING5, TRAF3IP3, CEP70, CCDC33, CARD9, PRDM14, ZNF250, UTP3, CTNNBL1, ZNF821, CDCA7L, TFPT, ABT1, PRPF31, PPP1R16B, EIF4A3, STX11, UBL4A, TADA2A, NOP2, MFAP1, MDFI, LMO1, DAXX, BYSL, ANKRD11, SUV39H1,
Protein Size: 420

Poids moléculaire: 46 kDa

ID gène: 55536

NCBI Accession: NM_001127370, NP_001120842

UniProt: B3KTR5