Pellino 1 anticorps (N-Term)
Aperçu rapide pour Pellino 1 anticorps (N-Term) (ABIN2787222)
Antigène
Voir toutes Pellino 1 (PELI1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- PELI1 Antibody - N-terminal region
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Séquence
- ESPIDFVVTD TVPGSQSNSD TQSVQSTISR FACRIICERN PPFTARIYAA
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against PELI1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PELI1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57429-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
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Autre désignation
- PELI1
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Sujet
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Background Information: PELI1 is an scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. PELI1 is required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.
Gene Name: Pellino E3 ubiquitin protein ligase 1
Alternative Symbols: DKFZp686C18116, MGC50990
Protein Name: E3 ubiquitin-protein ligase pellino homolog 1
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Poids moléculaire
- 46kDa
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ID gène
- 57162
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NCBI Accession
- NP_065702
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UniProt
- Q8C669
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Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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