ALS2 anticorps (Middle Region)
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- Antigène Voir toutes ALS2 Anticorps
- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ALS2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ALRGMSDLPP YGSGSSVQRQ EPPISRSAKY TFYKDPRLKD ATYDGRWLSG
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against ALS2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ALS2
- Top Product
- Discover our top product ALS2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1657 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
- Autre désignation
- ALS2 (ALS2 Produits)
- Synonymes
- anticorps als2, anticorps si:dkey-33m14.1, anticorps ALS2CR6, anticorps ALSJ, anticorps IAHSP, anticorps PLSJ, anticorps 3222402C23Rik, anticorps 9430073A21Rik, anticorps Als2cr6, anticorps Alsin, anticorps mKIAA1563, anticorps amyotrophic lateral sclerosis 2a (juvenile), anticorps alsin, anticorps ALS2, alsin Rho guanine nucleotide exchange factor, anticorps amyotrophic lateral sclerosis 2 (juvenile), anticorps als2a, anticorps CpipJ_CPIJ008258, anticorps CpipJ_CPIJ008260, anticorps ALS2, anticorps Als2
- Sujet
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The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ALS2CR6, ALSJ, FLJ31851, IAHSP, KIAA1563, MGC87187, PLSJ
Protein Interaction Partner: VCP, UBC, YWHAB,
Protein Size: 1657 - Poids moléculaire
- 184 kDa
- ID gène
- 57679
- NCBI Accession
- NM_020919, NP_065970
- UniProt
- Q96Q42
- Pathways
- Skeletal Muscle Fiber Development
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