WFDC1 anticorps (Middle Region)
Aperçu rapide pour WFDC1 anticorps (Middle Region) (ABIN2787263)
Antigène
Voir toutes WFDC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- VAEGIPNRGQ CVKQRRQADG RILRHKLYKE YPEGDSKNVA EPGRGQQKHF
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Homologie
- Dog: 86%, Human: 100%, Pig: 85%, Rat: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against WFDC1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human WFDC1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 220 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
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Autre désignation
- WFDC1
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Sujet
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This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81 % amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.
Alias Symbols: PS20
Protein Interaction Partner: EZR, ZNF677, RAB40B, FOSL1, XRCC2,
Protein Size: 220 -
Poids moléculaire
- 21 kDa
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ID gène
- 58189
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NCBI Accession
- NM_021197, NP_067020
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UniProt
- Q9HC57
Antigène
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