TMPRSS3 anticorps (N-Term)

N° du produit ABIN2787338

Détail du produit anti-TMPRSS3 anticorps

Antigène: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cheval, Chien, Cobaye, Boeuf (Vache), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMPRSS3 est non-conjugé

Application: Western Blotting (WB)

Séquence: MGENDPPAVE APFSFRSLFG LDDLKISPVA PDADAVAAQI LSLLPLKFFP

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TMPRSS3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 344 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TMPRSS3 (ABIN2787338)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." dans: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Détails sur TMPRSS3

Antigène: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Autre désignation: TMPRSS3 (TMPRSS3 Produits)

Synonymes: anticorps TMPRSS3, anticorps DKFZp469L1528, anticorps DFNB10, anticorps DFNB8, anticorps ECHOS1, anticorps TADG12, anticorps transmembrane protease, serine 3, anticorps TMPRSS3, anticorps Tmprss3

Sujet: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.
Alias Symbols: DFNB10, DFNB8, ECHOS1, TADG12
Protein Interaction Partner: TMED7, UBC, RXRA, EEF1A1,
Protein Size: 344

Poids moléculaire: 37 kDa

ID gène: 64699

NCBI Accession: NM_032405, NP_115781

UniProt: Q8WY52

Pathways: Sensory Perception of Sound