AXUD1 anticorps (Middle Region)
Aperçu rapide pour AXUD1 anticorps (Middle Region) (ABIN2787343)
Antigène
Voir toutes AXUD1 (CSRNP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- ARVQTHFIHT LTRLQLEQEA ESFRELEAPA QGSPPSPGEE ALVPTFPLAK
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against AXUD1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human AXUD1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 589 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AXUD1 (CSRNP1) (Cysteine-serine-Rich Nuclear Protein 1 (CSRNP1))
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Autre désignation
- AXUD1
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Sujet
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This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function.
Alias Symbols: DKFZp566F164, FAM130B, TAIP-3, URAX1, AXUD1, CSRNP-1
Protein Interaction Partner: TCEANC, ZNF417, ZNF587, PPP1CC, PPP1CA, AQP1, ELAVL1,
Protein Size: 589 -
Poids moléculaire
- 63 kDa
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ID gène
- 64651
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NCBI Accession
- NM_033027, NP_149016
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UniProt
- D6RBU1
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Pathways
- Platelet-derived growth Factor Receptor Signaling
Antigène
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