MFN1 anticorps (Middle Region)

N° du produit ABIN2787347

Détail du produit anti-MFN1 anticorps

Antigène: MFN1 (Mitofusin 1 (MFN1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cheval, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MFN1 est non-conjugé

Application: Western Blotting (WB)

Séquence: QVDITQKQLE EEIARLPKEI DQLEKIQNNS KLLRNKAVQL ENELENFTKQ

Homologie: Cow: 100%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MFN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MFN1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 741 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MFN1 (ABIN2787347)

Bonala, McFarlane, Ang, Lim, Lee, Chua, Lokireddy, Sreekanth, Leow, Meng, Shyong, Lee, Gluckman, Sharma, Kambadur: "Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity." dans: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 9, pp. 1518-35, (2013) (PubMed).

Papanicolaou, Khairallah, Ngoh, Chikando, Luptak, OShea, Riley, Lugus, Colucci, Lederer, Stanley, Walsh: "Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes." dans: Molecular and cellular biology, Vol. 31, Issue 6, pp. 1309-28, (2011) (PubMed).

Détails sur MFN1

Antigène: MFN1 (Mitofusin 1 (MFN1))

Autre désignation: MFN1 (MFN1 Produits)

Synonymes: anticorps mfn1, anticorps zgc:66150, anticorps mitofusin-1, anticorps MFN1, anticorps MFN2, anticorps hfzo1, anticorps hfzo2, anticorps 2310002F04Rik, anticorps 6330416C07Rik, anticorps D3Ertd265e, anticorps HR2, anticorps mKIAA4032, anticorps Fzo1b, anticorps mitofusin 1b, anticorps mitofusin 1, anticorps mitofusin 1 S homeolog, anticorps mfn1b, anticorps MFN1, anticorps mfn1.S, anticorps mfn1, anticorps Mfn1

Sujet: The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.
Alias Symbols: DKFZp762F247, FLJ20693, MGC41806, hfzo1, hfzo2
Protein Interaction Partner: PARK2, MARCH5, UBC, TER94, MAVS, CCNB1, ILF2, BAK1,
Protein Size: 741

Poids moléculaire: 84 kDa

ID gène: 55669

NCBI Accession: NM_033540, NP_284941

UniProt: Q8R4Z9