MFN1 anticorps (Middle Region)

N° du produit ABIN2787347

Cité dans 2 publications. Cet anticorps anti-MFN1 Polyclonal Lapin (ABIN2787347) détecte spécifiquement MFN1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Lapin, Cheval, Boeuf (Vache) et Porc.

Aperçu rapide pour MFN1 anticorps (Middle Region) (ABIN2787347)

Antigène: MFN1 (Mitofusin 1 (MFN1))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cheval, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MFN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MFN1 anticorps

Épitope: Middle Region

Fonction: MFN1 Antibody - middle region

Séquence: QVDITQKQLE EEIARLPKEI DQLEKIQNNS KLLRNKAVQL ENELENFTKQ

Homologie: Cow: 100%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MFN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MFN1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57702-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MFN1 (ABIN2787347)

Bonala, McFarlane, Ang, Lim, Lee, Chua, Lokireddy, Sreekanth, Leow, Meng, Shyong, Lee, Gluckman, Sharma, Kambadur: "Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity." dans: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 9, pp. 1518-35, (2013) (PubMed).

Papanicolaou, Khairallah, Ngoh, Chikando, Luptak, OShea, Riley, Lugus, Colucci, Lederer, Stanley, Walsh: "Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes." dans: Molecular and cellular biology, Vol. 31, Issue 6, pp. 1309-28, (2011) (PubMed).

Détails sur MFN1

Antigène: MFN1 (Mitofusin 1 (MFN1))

Autre désignation: MFN1

Sujet:

Background Information: The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.

Gene Name: Mitofusin 1

Alternative Symbols: hfzo1, hfzo2

Protein Name: Mitofusin-1

Poids moléculaire: 84 kDa

ID gène: 55669

NCBI Accession: NP_284941

UniProt: Q8R4Z9