MED16 anticorps (Middle Region)

N° du produit ABIN2787461

Cet anticorps anti-MED16 est un anticorps Lapin Polyclonal détectant MED16 dans WB. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour MED16 anticorps (Middle Region) (ABIN2787461)

Antigène: MED16 (Mediator Complex Subunit 16 (MED16))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED16 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MED16 anticorps

Épitope: Middle Region

Séquence: IVALSWLHNG VKLALHVEKS GASSFGEKFS RVKFSPSLTL FGGKPMEGWI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against MED16. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human MED16

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MED16

Antigène: MED16 (Mediator Complex Subunit 16 (MED16))

Autre désignation: MED16

Sujet: MED16 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. It mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Protein Interaction Partner: HECW2, CDK19, CDK8, UBC, MED19, MED26, EPAS1, FBXW7, MED11, MED8, MED29, MED9, MED18, MED4, RALY, MED13, MED12, MED24, MED21, MED14, MED1, CTDP1, HIST1H3A, MED10, MED25, MED15, VDR, TRA, MED28, OBFC1, ZC3H13, QKI, TADA2A, SUPT7L, SUPT3H, MYC, KAT2A, TRRAP
Protein Size: 663

Poids moléculaire: 72 kDa

ID gène: 10025

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha