CEBPA anticorps (C-Term)
Aperçu rapide pour CEBPA anticorps (C-Term) (ABIN2787466)
Antigène
Voir toutes CEBPA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- CEBPA Antibody - C-terminal region
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Séquence
- ASGGSGAGKA KKSVDKNSNE YRVRRERNNI AVRKSRDKAK QRNVETQQKV
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against CEBPA. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human CEBPA
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57938-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
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Autre désignation
- CEBPA
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Sujet
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Background Information: CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Gene Name: CCAAT/enhancer binding protein (C/EBP), alpha
Alternative Symbols: CEBP, C/EBP-alpha
Protein Name: CCAAT/enhancer-binding protein alpha
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Poids moléculaire
- 37kDa
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ID gène
- 1050
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NCBI Accession
- NP_004355
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UniProt
- P49715
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Pathways
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Antigène
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