CEBPB anticorps (N-Term)

N° du produit ABIN2787467

Cet anticorps anti-CEBPB Polyclonal Lapin (ABIN2787467) détecte spécifiquement CEBPB dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Boeuf (Vache), Porc, Chien et Lapin.

Aperçu rapide pour CEBPB anticorps (N-Term) (ABIN2787467)

Antigène: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Reactivité: Humain, Rat, Boeuf (Vache), Porc, Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEBPB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CEBPB anticorps

Épitope: N-Term

Fonction: CEBPB Antibody - N-terminal region

Séquence: AIDFSPYLEP LGAPQAPAPA TATDTFEAAP PAPAPAPASS GQHHDFLSDL

Homologie: Cow: 86%, Dog: 92%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CEBPB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57940-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CEBPB

Antigène: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Autre désignation: CEBPB

Sujet:

Background Information: CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: CCAAT/enhancer binding protein (C/EBP), beta

Alternative Symbols: TCF5, IL6DBP, NF-IL6, C/EBP-beta

Protein Name: CCAAT/enhancer-binding protein beta

Poids moléculaire: 36kDa

ID gène: 1051

NCBI Accession: NP_005185

UniProt: P17676

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation