MID1 anticorps (N-Term)
Aperçu rapide pour MID1 anticorps (N-Term) (ABIN2787522)
Antigène
Voir toutes MID1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- PTCRHVITLS QRGLDGLKRN VTLQNIIDRF QKASVSGPNS PSETRRERAF
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%
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Attributs du produit
- This is a rabbit polyclonal antibody against MID1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human MID1
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MID1 (Midline 1 (MID1))
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Autre désignation
- MID1
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Sujet
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The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse.
Protein Interaction Partner: STK36, MID2, UBE2E3, DYRK4, UBE2E2, UBE2E1, UBE2D3, UBE2D2, UBE2D1, PKN1, PPP2R4, PPP2CA, MID1, MEOX1, FKBP1A, EHHADH, BYSL, TCEANC, UBTD1, OTUB2, GMCL1, HTT, IGBP1, PNKP, MID1IP1, GNB2L1, RPS8, RPS3, NPM1, HSP90AA1, EEF1A1, ANXA2, UBC, UBE2D4, UBE2N, ELA
Protein Size: 552 -
Poids moléculaire
- 60 kDa
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ID gène
- 4281
Antigène
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