TRIM25 anticorps (Middle Region)

N° du produit ABIN2787550

Cet anticorps anti-TRIM25 Polyclonal Lapin (ABIN2787550) détecte spécifiquement TRIM25 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin et Cheval.

Aperçu rapide pour TRIM25 anticorps (Middle Region) (ABIN2787550)

Antigène: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM25 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRIM25 anticorps

Épitope: Middle Region

Fonction: TRIM25 Antibody - middle region

Séquence: LLDASETTST RKIKEEEKRV NSKFDTIYQI LLKKKSEIQT LKEEIEQSLT

Homologie: Cow: 79%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TRIM25. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TRIM25

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58105-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRIM25

Antigène: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Autre désignation: TRIM25

Sujet:

Background Information: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Gene Name: Tripartite motif containing 25

Alternative Symbols: EFP, Z147, RNF147, ZNF147

Protein Name: E3 ubiquitin/ISG15 ligase TRIM25

Poids moléculaire: 71kDa

ID gène: 7706

NCBI Accession: NP_005073

UniProt: Q14258