TRIM25 anticorps (Middle Region)

N° du produit ABIN2787550

Détail du produit anti-TRIM25 anticorps

Antigène: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Épitope: Middle Region

Reactivité: Humain, Souris, Boeuf (Vache), Rat, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM25 est non-conjugé

Application: Western Blotting (WB)

Séquence: LLDASETTST RKIKEEEKRV NSKFDTIYQI LLKKKSEIQT LKEEIEQSLT

Homologie: Cow: 79%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TRIM25. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TRIM25

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 630 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRIM25

Antigène: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Autre désignation: TRIM25 (TRIM25 Produits)

Synonymes: anticorps zgc:55773, anticorps MGC130751, anticorps EFP, anticorps RNF147, anticorps Z147, anticorps ZNF147, anticorps AA960166, anticorps AL022677, anticorps Zfp147, anticorps Efp, anticorps Znf147, anticorps E3 ubiquitin/ISG15 ligase TRIM25, anticorps tripartite motif containing 25, anticorps E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog, anticorps microRNA 3614, anticorps tripartite motif-containing 25, anticorps LOC100146440, anticorps trim25, anticorps LOC100490741.L, anticorps TRIM25, anticorps MIR3614, anticorps Trim25

Sujet: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Alias Symbols: EFP, RNF147, Z147, ZNF147
Protein Interaction Partner: UBC, DDX58, SUMO2, AMFR, UBE2D1, SUMO1, PCNA, USP15, UBA1, RPS27A, RPA1, KIF5B, HSPA1L, HSPA1B, HSPA1A, EEF1A2, ACLY, SUZ12, RNF2, EZH2, BMI1, HECW2, TRIM25, TRIM8, TFG, GRIK2, ESR1, OTUB2, USP39, VCP, WARS, UAP1, UBXN6, UBE2S, UBE2D2, TRAF6, ISG15, UBE2D
Protein Size: 630

Poids moléculaire: 71 kDa

ID gène: 7706

NCBI Accession: NM_005082, NP_005073

UniProt: Q14258