TNKS1BP1 anticorps (Middle Region)

N° du produit ABIN2787645

Détail du produit anti-TNKS1BP1 anticorps

Antigène: TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNKS1BP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: DGEASQTEDV DGTWGSSAAR WSDQGPAQTS RRPSQGPPAR SPSQDFSFIE

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TNKS1BP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TNKS1BP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1729 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TNKS1BP1

Antigène: TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))

Autre désignation: TNKS1BP1 (TNKS1BP1 Produits)

Synonymes: anticorps TAB182, anticorps Tab182, anticorps mKIAA1741, anticorps tankyrase 1 binding protein 1, anticorps 182 kDa tankyrase-1-binding protein, anticorps TNKS1BP1, anticorps LOC100625088, anticorps Tnks1bp1

Sujet: TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.
Alias Symbols: FLJ45975, KIAA1741, TAB182
Protein Interaction Partner: UBC, RNF219, SPC25, RABGEF1, DCTN3, SPTBN1, NLK, CSNK2A1, CNOT6L, CNOT6, VCP, HNRNPK, DYNC1H1, CBX3, SIRT7, TSG101, Cnot3, Capza1, TNKS2, TNKS,
Protein Size: 1729

Poids moléculaire: 190 kDa

ID gène: 85456

NCBI Accession: NM_033396, NP_203754

UniProt: Q9C0C2